Scott Suggs added 13 points and Desmond Simmons (12) and Aziz N'Diaye (11) each had double digit rebounding totals for Washington (12-5, 4-0 Pac-12) which won its fourth straight.
Spencer Dinwiddie finished with 15 points and Andre Roberson hung up a 10-point, 11-rebound double-double for Colorado (11-6, 1-4) which has lost four of its last five games.
Washington led 28-29 at the break despite shooting just 36.4 percent from the field by limiting Colorado to just seven first half field goals.
The Huskies struggled again in the second half, netting just 30.8 percent of their field goal attempts, but a 17-5 edge from the free-throw line allowed them to pull out the victory.
Colorado outscored Washington 32-18 on points in the paint but was on the short end of an 18-3 margin from 3-point range.
01/17 01:56:34 ET